Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221510 | 0.88 | ATM (0.65) | GSK3BATML3MBTL1KMT2AMEN1 | |
| SCHEMBL813536 | 0.87 | KMT2A (0.71) | GSK3BATML3MBTL1KMT2AMEN1 | |
| SCHEMBL1892189 | 0.84 | ATM (0.60) | GSK3BATML3MBTL1KMT2AMEN1 | |
| SCHEMBL9317594 | 0.84 | KMT2A (0.59) | GSK3BATML3MBTL1KMT2AMEN1 | |
| SCHEMBL7074293 | 0.84 | MEN1 (0.68) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL1500579 | 0.84 | KCNJ1 (0.68) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11843509 | 0.84 | KMT2A (0.59) | GSK3BATML3MBTL1KMT2AMEN1 | |
| SCHEMBL11309248 | 0.84 | MEN1 (0.68) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6771599 | 0.82 | ALDH1A1 (0.64) | GSK3BATML3MBTL1KMT2AMEN1 | |
| SCHEMBL9420481 | 0.82 | KMT2A (0.66) | GSK3BATML3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |