Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL22612697

Cc1ccnc(C)c1C.N

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 6/20 0.54
NOS3 P29474 5/20 0.54
CCR1 P32246 4/20 0.44
CCR5 P51681 4/20 0.44
CCR8 P51685 4/20 0.44
CYP2A6 P11509 1/20 0.39
UHRF1 Q96T88 1/20 0.35
PSMD14 O00487 1/20 0.34
COPS5 Q92905 1/20 0.34
PDE3B Q13370 2/20 0.33
PDE3A Q14432 2/20 0.33
MAOA P21397 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GRM4 Q14833 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7488 0.97
Hydrochloric Acid SCHEMBL1936574 0.94 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
Fluoride SCHEMBL2020932 0.94 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
Hydrochloric Acid SCHEMBL27389327 0.94 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
SCHEMBL29125217 0.94
Bromide SCHEMBL10623434 0.94 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
Iodide SCHEMBL11070568 0.94 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
Iodide SCHEMBL27713885 0.94 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
SCHEMBL28159018 0.92 NOS2 (0.52) NOS2NOS3CCR1CCR5CCR8
SCHEMBL28167987 0.87 NOS2 (0.48) NOS2NOS3CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 CN claimed
CN-115052914-B Shelf life-extended bulk polymerized polycycloolefin compositions as optical materials 住友电木株式会社 2023-06-30 CN claimed
CN-115052914-A Shelf life extended bulk polymerized polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-09-13 CN claimed
CN-114938648-A Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same 普罗米鲁斯有限责任公司 2022-08-23 CN claimed
CN-114144450-A Stable polycycloolefin polymers and inorganic nanocomposites as optical materials 普罗米鲁斯有限责任公司 2022-03-04 CN claimed
CN-116848170-A Photoactive bulk polymerized polycycloolefin compositions as optical materials that are shelf-life stable for extended periods of time 普罗米鲁斯有限责任公司 2023-10-03 CN disclosed
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 CN disclosed
CN-115052914-B Shelf life-extended bulk polymerized polycycloolefin compositions as optical materials 住友电木株式会社 2023-06-30 CN disclosed
CN-115052914-A Shelf life extended bulk polymerized polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-09-13 CN disclosed
CN-114938648-A Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same 普罗米鲁斯有限责任公司 2022-08-23 CN disclosed
CN-114144450-A Stable polycycloolefin polymers and inorganic nanocomposites as optical materials 普罗米鲁斯有限责任公司 2022-03-04 CN disclosed
US-10968223-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2021-04-06 US disclosed
US-20200347059-A1 IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS PROXIMAGEN, LLC (US) 2020-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968223-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PNPO, PPOX, SCO2 NOS2 233/4885NOS3 179/4885CCR1 3777/4885
US-20200347059-A1 IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS PNPO, PPOX, SCO2 NOS2 233/4885NOS3 179/4885CCR1 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.