SCHEMBL226186

SCHEMBL226186

CC(C)(C)c1[c]ccc(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
TSHR P16473 1/20 0.33
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
NPC1 O15118 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28147188 0.98 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL27409495 0.98 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL28007764 0.98 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL28206151 0.98 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL28050955 0.98 ALDH1A1 (0.37) ALDH1A1HPGDALOX15HSD17B10TDP1
Water SCHEMBL28653636 0.96 ALDH1A1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL4470598 0.88 ESR1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL26106158 0.88 ALDH1A1 (0.35) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL11272457 0.85 KIF11 (0.39) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL9296691 0.85 KIF11 (0.39) ALDH1A1MEN1KMT2ATSHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4908 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063795-B High-gloss high-toughness polypropylene composition and polypropylene material prepared from same 中国石油化工股份有限公司 2024-07-05 CN claimed
US-20240216900-A1 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-07-04 US claimed
CN-118231023-A Composite conductive particles, polyphenyl ether composite and preparation method thereof 深圳烯湾科技有限公司 2024-06-21 CN claimed
CN-117983300-A Catalyst containing N-triptycene ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117983304-A Catalyst containing tetraphosphine ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117983302-A Catalyst containing ferrocene PNP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117983305-A Catalyst containing aromatic heterocycle-aliphatic ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117983299-A PNNP-F ligand-containing catalyst for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117983306-A Catalyst containing PCCP ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
CN-117983301-A PNNP-aliphatic ligand-containing ethylene selective tetramerization catalyst and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
US-4526864-A Silver halide emulsion, cyan couplers KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-07-02 US claimed
EP-0115885-A1 Stabilized polymer composition STAMICARBON B.V. (NL) 1984-08-15 EP claimed
EP-0113124-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1984-07-11 EP claimed
EP-0085404-A1 Stabilized linear low density polyethylene BORG-WARNER CHEMICALS INC. (US) 1983-08-10 EP claimed
EP-0002821-B1 CYCLIC PHOSPHITES AND ORGANIC MATERIAL STABILIZED BY THEM CIBA-GEIGY AG (CH) 1982-06-23 EP claimed
US-4263230-A ANTIOXIDANTS FOR POLYMERS STAUFFER CHEMICAL COMPANY (US) 1981-04-21 US claimed
US-4196117-A Alkylated 1,1'-biphenyl-2,2'-diyl phosphites and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-04-01 US claimed
US-4093587-A Trisubstituted hydroxyphenylalkanoic acid ester and amide stabilized compositions CIBA-GEIGY CORPORATION (US) 1978-06-06 US claimed
US-4048367-A SUBTITUTED PHENOL NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1977-09-13 US claimed
US-3984460-A LIGHT AND HEAT STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-10-05 US claimed