Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25079011 | 0.86 | CHRM2 (0.43) | CHRM2CHRM1CHRM3NR1H2RORC | |
| SCHEMBL18598985 | 0.86 | NR1H2 (0.42) | CHRM2CHRM1CHRM3NR1H2RORC | |
| SCHEMBL31279010 | 0.86 | NR1H2 (0.42) | CHRM2CHRM1CHRM3NR1H2RORC | |
| SCHEMBL22620477 | 0.83 | NR1H2 (0.40) | CHRM2CHRM1CHRM3NR1H2RORC | |
| SCHEMBL16903486 | 0.81 | CHRM2 (0.53) | CHRM2CHRM1CHRM3NR1H2HPGD | |
| SCHEMBL25078967 | 0.81 | CHRM2 (0.53) | CHRM2CHRM1CHRM3NR1H2HPGD | |
| SCHEMBL16903484 | 0.81 | CHRM2 (0.53) | CHRM2CHRM1CHRM3NR1H2HPGD | |
| SCHEMBL22620485 | 0.80 | HPGD (0.40) | NR1H2RORCHPGDUSP2SMN1; SMN2 | |
| SCHEMBL14494 | 0.78 | HPGD (0.53) | CHRM2CHRM1CHRM3NR1H2HPGD | |
| SCHEMBL241055 | 0.78 | HPGD (0.53) | CHRM2CHRM1CHRM3NR1H2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020221294-A1 | BRIDGE RING-3,4-DIHYDRO-PYRIDO[1,2-A]PYRAZINE-1,8-DIONE COMPOUND AND PHARMACEUTICAL USE THEREOF | 上海拓界生物医药科技有限公司 | 2020-11-05 | — | — | WO | disclosed |