Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 7/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410190 | 0.87 | TGFBR1 (0.43) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL29547981 | 0.85 | QRFPR (0.42) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL29987730 | 0.85 | QRFPR (0.42) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL30754137 | 0.85 | QRFPR (0.42) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL30220824 | 0.84 | QRFPR (0.42) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL31423993 | 0.83 | TGFBR1 (0.40) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL30956646 | 0.83 | TGFBR1 (0.40) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL31383401 | 0.83 | QRFPR (0.41) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL31424011 | 0.83 | TGFBR1 (0.40) | TGFBR1MMENMT2NMT1QRFPR | |
| SCHEMBL30956647 | 0.83 | TGFBR1 (0.40) | TGFBR1MMENMT2NMT1QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445758-B1 | DIPROVOCIMS: A NEW AND POTENT CLASS OF TLR AGONISTS | SCRIPPS RESEARCH INST (US) | 2020-11-04 | — | — | EP | disclosed |