SCHEMBL22623141

SCHEMBL22623141

CC(C)(C)[Si](O[C@H]1C[C@H](N2C(=O)c3ccccc3C2=O)CC1N=[N+]=[N-])(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22228040 1.00 L3MBTL1 (0.31) L3MBTL1
SCHEMBL20832767 0.82 L3MBTL1 (0.34) L3MBTL1
SCHEMBL22227921 0.81 L3MBTL1 (0.34) L3MBTL1
SCHEMBL20832770 0.81 L3MBTL1 (0.34) L3MBTL1
SCHEMBL33374588 0.81 L3MBTL1 (0.34) L3MBTL1
SCHEMBL22227917 0.77 L3MBTL1 (0.38) L3MBTL1
SCHEMBL22227918 0.77 L3MBTL1 (0.38) L3MBTL1
SCHEMBL22228058 0.74 L3MBTL1 (0.36) L3MBTL1
SCHEMBL30602670 0.74 L3MBTL1 (0.36) L3MBTL1
SCHEMBL17522167 0.74 BACE1 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331700-A1 COMPOUND HAVING CYCLIC STRUCTURE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-10-19 — — US disclosed
US-20200347030-A1 COMPOUND HAVING CYCLIC STRUCTURE DAIICHI SANKYO COMPANY, LIMITED (JP) 2020-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200347030-A1 COMPOUND HAVING CYCLIC STRUCTURE H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ECE1, IL1B L3MBTL1 3800/4885
US-20230331700-A1 COMPOUND HAVING CYCLIC STRUCTURE H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ECE1, IL1B L3MBTL1 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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