Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.62 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443189 | 0.85 | MAPT (0.63) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL17395843 | 0.82 | MAPT (0.65) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL22624755 | 0.82 | MAPT (0.60) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL10182503 | 0.82 | MAPT (0.65) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL17395842 | 0.82 | MAPT (0.65) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL14237845 | 0.82 | MAPT (0.60) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL17395868 | 0.82 | MAPT (0.65) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL22624798 | 0.81 | MAPT (0.59) | MAPTMEN1KMT2AFNTAFNTB | |
| SCHEMBL7262435 | 0.80 | MEN1 (0.59) | MAPTAPAF1ATMSAE1UBA2 | |
| SCHEMBL7262438 | 0.80 | MEN1 (0.59) | MAPTAPAF1ATMSAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317076-A9 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-10-14 | — | — | US | disclosed |
| US-20200347010-A1 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | UNIV HONG KONG POLYTECHNIC (CN) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347010-A1 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | CFTR, FPR3, FPR1 | MAPT 4046/4885APAF1 1634/4885ATM 4631/4885 |
| US-20210317076-A9 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | CFTR, FPR3, FPR1 | MAPT 4046/4885APAF1 1634/4885ATM 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.