Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24519307 | 0.95 | RAD52 (0.37) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL22626394 | 0.90 | NR1H4 (0.31) | NR1H4 | |
| SCHEMBL17789663 | 0.89 | RAD52 (0.37) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL16377982 | 0.89 | RAD52 (0.37) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL16377775 | 0.89 | RAD52 (0.36) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL22626617 | 0.88 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL16377938 | 0.87 | RAD52 (0.35) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL22626505 | 0.87 | NR1H4 (0.38) | RAD52NR1H4 | |
| SCHEMBL29670686 | 0.87 | RAD52 (0.35) | RAD52CCNA2CDK2CCNA1 | |
| SCHEMBL17783210 | 0.87 | CCNA2 (0.33) | RAD52CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |