Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377938 | 0.93 | RAD52 (0.35) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL16377982 | 0.92 | RAD52 (0.37) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL16377775 | 0.92 | RAD52 (0.36) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL17783208 | 0.90 | RAD52 (0.33) | RAD52CCNA2CDK2CCNA1TP53 | |
| SCHEMBL16377842 | 0.90 | CNR1 (0.36) | RAD52CDK2ALDH1A1CNR1KMT2A | |
| SCHEMBL17783210 | 0.88 | CCNA2 (0.33) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL16377978 | 0.88 | KMT2A (0.34) | RAD52ALDH1A1ACKR3KDM4EKMT2A | |
| SCHEMBL16377937 | 0.87 | CCNA2 (0.32) | RAD52CCNA2CDK2CCNA1 | |
| SCHEMBL16377972 | 0.87 | RAD52 (0.33) | RAD52CCNA2CDK2CCNA1MAPT | |
| SCHEMBL24519307 | 0.87 | RAD52 (0.37) | RAD52CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | MERCK PATENT GMBH (DE) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | FSHR, GNRHR, LHCGR | RAD52 4685/4885CCNA2 4041/4885CDK2 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.