Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22626368 | 0.95 | RAD52 (0.37) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL22626505 | 0.91 | NR1H4 (0.38) | RAD52NR1H4 | |
| SCHEMBL24519317 | 0.90 | NR1H4 (0.31) | NR1H4 | |
| SCHEMBL17789663 | 0.89 | RAD52 (0.37) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL16377775 | 0.89 | RAD52 (0.36) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL16377982 | 0.89 | RAD52 (0.37) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL16377938 | 0.87 | RAD52 (0.35) | RAD52NR1H4CCNA2CDK2CCNA1 | |
| SCHEMBL29670686 | 0.87 | RAD52 (0.35) | RAD52CCNA2CDK2CCNA1 | |
| SCHEMBL17783210 | 0.87 | CCNA2 (0.33) | RAD52CCNA2CDK2CCNA1 | |
| SCHEMBL17783208 | 0.85 | RAD52 (0.33) | RAD52CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | MERCK PATENT GMBH (DE) | 2022-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365199-B2 | Pyrazole compounds as modulators of FSHR and uses thereof | FSHR, GNRHR, LHCGR | RAD52 4685/4885NR1H4 857/4885CCNA2 4041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.