Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735738 | 0.90 | SIGMAR1 (0.37) | SIGMAR1APPTHRBNAMPTCYP19A1 | |
| SCHEMBL21735560 | 0.89 | THRB (0.43) | SIGMAR1THRBMAPTKDM4EALDH1A1 | |
| SCHEMBL21734956 | 0.89 | SIGMAR1 (0.40) | SIGMAR1APPTHRBNAMPTCYP19A1 | |
| SCHEMBL21735359 | 0.88 | SIGMAR1 (0.38) | SIGMAR1APPNAMPTCYP19A1MAPT | |
| SCHEMBL22628923 | 0.87 | CYP2E1 (0.32) | CYP19A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL21735100 | 0.86 | APP (0.37) | SIGMAR1APPCYP19A1MAPTKDM4E | |
| SCHEMBL21735790 | 0.83 | HDAC1 (0.37) | THRBNAMPTCYP19A1MAPTKDM4E | |
| SCHEMBL21735390 | 0.82 | THRB (0.39) | SIGMAR1THRBMAPTKDM4EALDH1A1 | |
| SCHEMBL21735223 | 0.82 | CYP19A1 (0.36) | SIGMAR1APPCYP19A1MAPTKDM4E | |
| SCHEMBL22625065 | 0.81 | NPC1 (0.54) | MAPTKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |