Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735230 | 0.90 | ALDH1A1 (0.32) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL21735425 | 0.87 | GLA (0.33) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL21735231 | 0.86 | RAB9A (0.33) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL22629978 | 0.81 | APP (0.33) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL22629977 | 0.80 | APP (0.33) | — | |
| SCHEMBL21735300 | 0.79 | S1PR1 (0.33) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL21735838 | 0.78 | ALDH1A1 (0.34) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL21735094 | 0.76 | PTPN1 (0.33) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL21734959 | 0.75 | S1PR1 (0.37) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL22630018 | 0.74 | F2RL3 (0.36) | KDM4EALDH1A1TP53GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |