Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735545 | 0.82 | MTNR1A (0.39) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL21735706 | 0.81 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL21735802 | 0.75 | LMNA (0.33) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL21735799 | 0.73 | PSEN1 (0.46) | MTNR1AMTNR1BALDH1A1PSEN1PSEN2 | |
| SCHEMBL26292361 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL22630103 | 0.72 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL22629969 | 0.72 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL21735403 | 0.71 | MTNR1A (0.38) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL21735533 | 0.71 | GRIK1 (0.58) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL22593848 | 0.71 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |