Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2262951 | 1.00 | CNR1 (0.52) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL3714605 | 0.99 | CNR1 (0.55) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL3714602 | 0.99 | CNR1 (0.55) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL2261441 | 0.99 | CNR1 (0.51) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL2261434 | 0.99 | CNR1 (0.51) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL3721499 | 0.97 | CNR1 (0.53) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL3721495 | 0.97 | CNR1 (0.53) | CNR1CNR2KDM4EFASNFAAH | |
| SCHEMBL6572506 | 0.86 | CNR1 (0.51) | CNR1CNR2KDM4EFASNFAAH | |
| (2E,4Z-Decadienoyl)Pyrrolidine SCHEMBL988489 | 0.77 | KDM4E (0.48) | CNR1CNR2KDM4EFASNALDH1A1 | |
| Sarmentine SCHEMBL988355 | 0.77 | KDM4E (0.48) | CNR1CNR2KDM4EFASNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036383-A3 | USE OF A PROTEIN TYROSINE KINASE INHIBITOR FOR INDUCING THE DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARDIOGENIC CELLS | 파미셀 주식회사 (KR) | 2012-05-10 | — | — | WO | disclosed |
| EP-1927587-B1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 2011-12-07 | — | — | EP | disclosed |
| US-8007841-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-8007840-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-8007839-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES (US) | 2011-08-30 | — | — | US | disclosed |
| EP-1520850-B1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1927587-A2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2008-06-04 | — | — | EP | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20080008810-A1 | CONJUGATED DIENAMIDES, METHODS OF PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAME AND USES THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-01-10 | — | — | US | disclosed |
| US-20080008811-A1 | CONJUGATED DIENAMIDES, METHODS OF PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAME AND USES THEREOF | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-01-10 | — | — | US | disclosed |
| US-20050075368-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC.WW | 2005-04-07 | — | — | US | disclosed |
| US-20050074533-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2005-04-07 | — | — | US | disclosed |
| EP-1520850-A2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075368-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | TAS2R41, TAS2R42, TAS2R14 | CNR1 1556/4885CNR2 1265/4885KDM4E 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.