Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22631953 | 0.80 | — | — | |
| SCHEMBL19285950 | 0.80 | SHBG (0.35) | — | |
| SCHEMBL19285946 | 0.78 | SHBG (0.34) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL8352192 | 0.72 | SHBG (0.50) | SLC6A2TAAR1HTR2ASLC6A4HRH1 | |
| SCHEMBL14685564 | 0.72 | TAAR1 (0.39) | SLC6A2TAAR1HTR2AHTR2B | |
| SCHEMBL18510155 | 0.70 | TAAR1 (0.41) | SLC6A2TAAR1HTR2AHTR2B | |
| SCHEMBL22448845 | 0.69 | — | — | |
| SCHEMBL22448853 | 0.68 | TAAR1 (0.39) | SLC6A2TAAR1 | |
| SCHEMBL2176867 | 0.67 | — | — | |
| SCHEMBL23221272 | 0.67 | SHBG (0.45) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2052011-B1 | TARGETED POLYLYSINE DENDRIMER THERAPEUTIC AGENT | STARPHARMA PTY LTD (AU) | 2020-11-04 | — | — | EP | disclosed |