SCHEMBL2263254

SCHEMBL2263254

Nc1cccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
MAPK1 P28482 1/20 0.59
CYP3A4 P08684 2/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
PTGS1 P23219 3/20 0.36
ALDH1A1 P00352 4/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA14 Q9ULX7 1/20 0.34
MAOA P21397 1/20 0.33
NOS1 P29475 1/20 0.32
HTR1A P08908 1/20 0.32
MAOB P27338 2/20 0.32
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651762 1.00 TSHR (0.59) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL15319724 1.00 TSHR (0.59) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL24710719 0.98 TSHR (0.61) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL8974219 0.94 TSHR (0.65) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29405287 0.94 TSHR (0.65) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL8167656 0.92 TSHR (0.63) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29402206 0.88 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL3843446 0.88 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL3867382 0.84 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL10714404 0.83 TSHR (0.74) TSHRMAPK1CYP3A4CASP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111495272-A Efficient emulsifier composition and application thereof 京准化工技术(上海)有限公司 2020-08-07 CN disclosed
US-9680156-B2 Composition, polymer thereof, electrode and electrolyte membrane for fuel cell, and fuel cell including the same SAMSUNG ELECTRONICS CO., LTD (KR) 2017-06-13 US disclosed
US-20160122187-A1 Process for Covalently Grafting a Carbonaceous Material TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2016-05-05 US disclosed
EP-2997092-A1 PROCESS FOR COVALENTLY GRAFTING A CARBONACEOUS MATERIAL Total Research & Technology Feluy (BE) 2016-03-23 EP disclosed
US-20150311537-A1 COMPOSITION, POLYMER THEREOF, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL, AND FUEL CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-29 US disclosed
US-9112232-B2 Composition, polymer thereof, electrode and electrolyte membrane for fuel cell, and fuel cell including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-18 US disclosed
WO-2014184330-A1 PROCESS FOR COVALENTLY GRAFTING A CARBONACEOUS MATERIAL TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2014-11-20 WO disclosed
US-20110195340-A1 COMPOSITION, POLYMER THEREOF, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL, AND FUEL CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO. LTD (KR) 2011-08-11 US disclosed
EP-1004925-B1 Polyimide photo alignment film from 3,3',4,4'-benzophenone tetracarboxylic dianhydride and ortho-substituted aromatic diamines for liquid crystal displays DU PONT (US) 2007-07-11 EP disclosed
EP-1222237-B1 MATERIALS FOR INDUCING ALIGNMENT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ELSICON INC (US) 2007-04-11 EP disclosed
US-6194039-B1 POLYIMIDES, POLYAMIC ACIDS ELSICON, INC. 2001-02-27 US disclosed
US-6139926-A Polyimide photo alignment film from 3,3,4,4-benzophenone tetracarboxylic dianhydride and ortho-substituted aromatic diamines for liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-10-31 US disclosed
EP-1004925-A2 Polyimide photo alignment film from 3, 3'4,4'-Benzophenone tetracarboxylic dianhydride and ortho-substituted aromatic diamines for liquid crystal displays E. I. du Pont de Nemours and Company (US) 2000-05-31 EP disclosed
US-5759442-A Polyimide alignment film from 2,2-BIS (3,4-dicarboxyphenyl)--hexafluoropropane dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-02 US disclosed
EP-0768559-A1 Polyimide alignment film from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-16 EP disclosed
EP-0507293-B1 Liquid crystal displays of high tilt bias angles DU PONT (US) 1995-10-11 EP disclosed
US-5186985-A Polyimide layer comprises of an acid dianhydride and diamine with pendant perfluorinated chain E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-16 US disclosed
EP-0280156-B1 PROCESS FOR THE PREPARATION OF ACETOACETYLARYLAMIDES-HETEROARYLAMIDES RESPECTIVELY OF DEACTIVED AROMATIC COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-11 EP disclosed
EP-0507293-A2 Liquid crystal displays of high tilt bias angles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-07 EP disclosed
EP-0280156-A2 Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150311537-A1 COMPOSITION, POLYMER THEREOF, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL, AND FUEL CELL INCLUDING THE SAME PEF1, FERMT2, PHOSPHO1 TSHR 4220/4885MAPK1 945/4885CYP3A4 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.