Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22636087 | 0.70 | — | — | |
| SCHEMBL5217485 | 0.66 | BCHE (0.35) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11044814 | 0.62 | GAA (0.33) | — | |
| SCHEMBL11784129 | 0.59 | SLC6A2 (0.44) | — | |
| SCHEMBL6439468 | 0.59 | KDM4E (0.42) | GNAI3GNAO1GNAI1 | |
| SCHEMBL613082 | 0.58 | CYP4F2 (0.38) | — | |
| SCHEMBL5736616 | 0.58 | L3MBTL1 (0.34) | GNAI3GNAO1GNAI1 | |
| SCHEMBL9603340 | 0.58 | GNAI3 (0.41) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7197775 | 0.57 | CYP4F2 (0.41) | — | |
| SCHEMBL5031163 | 0.57 | CYP4F2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3965766-A1 | COMBINATION OF AN ?2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2022-03-16 | — | — | EP | disclosed |
| WO-2020225185-A1 | COMBINATION OF AN α2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-12 | — | — | WO | disclosed |