Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584201 | 0.91 | NSD2 (0.44) | NSD2GRM4CYP1A2CYP2C19ALOX15 | |
| SCHEMBL20581197 | 0.80 | NSD2 (0.39) | NSD2GRM4CYP1A2CYP2C19ALOX15 | |
| SCHEMBL6713545 | 0.80 | NSD2 (0.39) | NSD2GRM4CYP1A2CYP2C19ALOX15 | |
| Cycloleucine SCHEMBL21462057 | 0.78 | NSD2 (0.50) | NSD2GRM4CYP1A2CYP2C19ALOX15 | |
| 1-Aminocyclobutane Carboxylic Acid SCHEMBL61734 | 0.78 | — | — | |
| Cycloleucine SCHEMBL8495 | 0.78 | — | — | |
| SCHEMBL21423145 | 0.76 | NSD2 (0.48) | NSD2GRM4CYP1A2CYP2C19ALOX15 | |
| Cycloleucine SCHEMBL3674853 | 0.76 | NSD2 (0.48) | NSD2GRM4CYP1A2CYP2C19ALOX15 | |
| 1-Aminocyclobutane Carboxylic Acid SCHEMBL4949098 | 0.76 | — | — | |
| Cycloleucine SCHEMBL1704308 | 0.76 | NSD2 (0.48) | NSD2GRM4CYP1A2CYP2C19ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015932-A1 | BIOORTHOGONAL COMPOSITIONS | TAMBO, INC. | 2021-01-21 | — | — | US | disclosed |
| US-10828373-B2 | Bioorthogonal compositions | TAMBO, INC. (US) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828373-B2 | Bioorthogonal compositions | CD47, EPHA2, MSN | NSD2 2839/4885GRM4 3854/4885CYP1A2 3560/4885 |
| US-20210015932-A1 | BIOORTHOGONAL COMPOSITIONS | CD47, EPHA2, MSN | NSD2 2839/4885GRM4 3854/4885CYP1A2 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.