Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.60 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639799 | 1.00 | LMNA (1.00) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL4077665 | 0.84 | ALDH1A1 (0.78) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL12933266 | 0.81 | LMNA (0.69) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1874466 | 0.80 | LMNA (0.72) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL23052424 | 0.79 | NPY5R (0.69) | LMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1423782 | 0.79 | ALDH1A1 (0.79) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL4763389 | 0.79 | ALDH1A1 (0.79) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL19264910 | 0.79 | SLC12A2 (0.92) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL3079952 | 0.79 | ALDH1A1 (0.79) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13297977 | 0.79 | SLC12A2 (0.92) | LMNAHTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | LMNA 769/4885HTT 488/4885KMT2A 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.