Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22639804 | 0.83 | MAPT (0.62) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519620 | 0.77 | MAPT (0.53) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519616 | 0.77 | MAPT (0.53) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519445 | 0.75 | KMT2A (0.52) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519447 | 0.75 | KMT2A (0.52) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519560 | 0.74 | KMT2A (0.70) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519562 | 0.74 | KMT2A (0.70) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL880195 | 0.73 | GAA (0.75) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519664 | 0.72 | KMT2A (0.58) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 | |
| SCHEMBL21519665 | 0.72 | KMT2A (0.58) | ALDH1A1SMN1; SMN2MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | ALDH1A1 1636/4885SMN1; SMN2 2515/4885MAPT 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.