Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | EDNRB | P24530 | 2/20 | 0.48 |
| ▸ | EDNRA | P25101 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498694 | 0.86 | MAPT (0.59) | KMT2AMAPTTHRBGAACYP19A1 | |
| SCHEMBL22640138 | 0.82 | NPC1 (0.57) | MAPTHTTTHRBKCNJ1ALDH1A1 | |
| SCHEMBL22640139 | 0.82 | NPC1 (0.57) | MAPTHTTTHRBKCNJ1ALDH1A1 | |
| SCHEMBL22640166 | 0.72 | ALDH1A1 (0.56) | KMT2AMAPTHTTTHRBKCNJ1 | |
| SCHEMBL5960116 | 0.71 | MEN1 (0.73) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL22639780 | 0.70 | KDM1A (0.48) | MAPTCYP2C19CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL6505407 | 0.69 | ALDH1A1 (0.68) | MEN1KMT2ACYP2C9CYP19A1ALDH1A1 | |
| SCHEMBL15841263 | 0.69 | SMN1; SMN2 (0.61) | MAPTHTTLMNAGAAALDH1A1 | |
| SCHEMBL3885557 | 0.69 | MAPT (0.55) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL1287434 | 0.68 | ALDH1A1 (0.70) | MEN1KMT2ACYP1A2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | MEN1 935/4885KMT2A 4613/4885MAPT 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.