Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453950 | 0.71 | KDM4E (0.56) | PRKCIMEN1MAPTHTTGSK3B | |
| SCHEMBL5190758 | 0.69 | SPR (0.52) | PRKCIACHEMEN1MAPT | |
| SCHEMBL5684882 | 0.65 | AXL (0.59) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL29358019 | 0.64 | PRKCI (0.61) | PRKCIACHEMEN1MAPTHTT | |
| SCHEMBL30597925 | 0.64 | PRKCI (0.61) | PRKCIACHEMEN1MAPTHTT | |
| SCHEMBL111004 | 0.64 | PRKCI (0.61) | PRKCIACHEMEN1MAPTHTT | |
| Hydrochloric Acid SCHEMBL5687723 | 0.64 | AXL (0.58) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL3265555 | 0.64 | PRKCI (0.44) | PRKCIACHEMEN1MAPTHTT | |
| SCHEMBL4638442 | 0.63 | — | — | |
| SCHEMBL7685483 | 0.63 | KDM4E (0.47) | AXLMKNK1MKNK2MEN1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011085140-A1 | THICKENED HAIR COLOURANT AND BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| US-7204861-B2 | Hair coloring compositions | THE PROCTER & GAMBLE COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| US-20040237218-A1 | Hair colouring compositions | WELLA OPERATIONS US, LLC | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040237218-A1 | Hair colouring compositions | COXFA4L2, CYBA, MT-CO3 | PRKCI 3579/4885ACHE 2542/4885AXL 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.