Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453950 | 0.86 | KDM4E (0.56) | SPRKDM4EL3MBTL1RAB9AGAA | |
| SCHEMBL7685483 | 0.73 | KDM4E (0.47) | KDM4EL3MBTL1RAB9ANPC1GAA | |
| SCHEMBL3906088 | 0.71 | TAAR1 (0.50) | SPRRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3906998 | 0.70 | SPR (0.49) | SPRKDM4ERAB9APABPC1ALDH1A1 | |
| SCHEMBL4625444 | 0.70 | PRKCI (0.46) | KDM4EL3MBTL1RAB9ANPC1PRKCI | |
| SCHEMBL2264310 | 0.69 | PRKCI (0.40) | PRKCIACHEMAPTMEN1 | |
| SCHEMBL25442716 | 0.69 | MEN1 (0.57) | KDM4ERAB9ANPC1KCNMA1CASP6 | |
| SCHEMBL4383419 | 0.69 | RAB9A (0.50) | SPRKDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL4572901 | 0.69 | RAB9A (0.50) | SPRRAB9ANPC1GAAPABPC1 | |
| SCHEMBL3254598 | 0.69 | KDM4E (0.59) | KDM4EL3MBTL1RAB9ANPC1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361851-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2007-02-21 | — | — | EP | disclosed |
| CN-1264498-C | Primary intermediates for oxidative dyeing of hair | PROCTER & GAMBLE (US) | 2006-07-19 | — | — | CN | disclosed |
| US-7070630-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| CN-1607935-A | Primary intermediates for oxidative dyeing of hair | PROCTER & GAMBLE (US) | 2005-04-20 | — | — | CN | disclosed |
| EP-1361851-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-6750339-B2 | SUCH AS 4-AMINO-2-(2-DIMETHYLAMINO-ETHYL)-PHENOL; USEFUL IN PLACE OF P-AMINOPHENOL | THE PROCTER AND GAMBLE COMPANY | 2004-06-15 | — | — | US | disclosed |
| EP-1361851-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G-Clairol, Inc. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-17 | — | — | US | disclosed |
| WO-2002058653-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | SPR 976/4885KDM4E 4096/4885L3MBTL1 3908/4885 |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | SPR 976/4885KDM4E 4096/4885L3MBTL1 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.