SCHEMBL22644244

SCHEMBL22644244

CC(C)N(C(=O)N1CCCCCC1=O)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
MITF O75030 1/20 0.44
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.39
STAT6 P42226 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 3/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
THRB P10828 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
PIK3CD O00329 1/20 0.34
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22648829 0.80 LMNA (0.46) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL18566 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL8382041 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL30307790 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL15071000 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL15061890 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL15061902 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL8379280 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL15061896 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6
SCHEMBL8380680 0.75 SMN1; SMN2 (0.50) SMN1; SMN2MITFLMNAMAPTSTAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354594-A1 THERMALLY REVERSIBLE AND REORGANIZABLE CROSSLINKING POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
WO-2020227296-A1 THERMALLY REVERSIBLE AND REORGANIZABLE CROSSLINKING POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2020-11-12 WO disclosed