SCHEMBL22644247

SCHEMBL22644247

CC(C)N(C(=O)N1C(=O)CCC1=O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 2/20 0.41
P2RX1 P51575 1/20 0.41
P2RX3 P56373 1/20 0.41
P2RX7 Q99572 1/20 0.41
BCHE P06276 1/20 0.40
MAPT P10636 1/20 0.35
ACE P12821 2/20 0.32
MME P08473 1/20 0.32
POLB P06746 1/20 0.32
SLC1A2 P43004 1/20 0.31
DPP4 P27487 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22648841 0.87 P2RX4 (0.33) P2RX4P2RX1P2RX3P2RX7BCHE
SCHEMBL22644258 0.82
SCHEMBL18485451 0.78 P2RX4 (0.38) P2RX4BCHEMAPT
SCHEMBL22648825 0.73 P2RX4 (0.30) P2RX4
SCHEMBL10606912 0.73 CHRNB2 (0.34) MAPTACESLC1A2
SCHEMBL22644244 0.70 SMN1; SMN2 (0.44) MAPTPOLB
SCHEMBL887169 0.69 NOTUM (0.42) POLB
SCHEMBL23733173 0.68 CA12 (0.34)
SCHEMBL198304 0.68 CA12 (0.34)
SCHEMBL21459165 0.67 ACE (0.30) MAPTACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354594-A1 THERMALLY REVERSIBLE AND REORGANIZABLE CROSSLINKING POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
WO-2020227296-A1 THERMALLY REVERSIBLE AND REORGANIZABLE CROSSLINKING POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2020-11-12 WO disclosed