Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22644287 | 1.00 | KMT2A (0.33) | KMT2ATSHRALDH1A1POLBMAPK1 | |
| SCHEMBL23943822 | 0.89 | EGLN2 (0.40) | KMT2ATSHRALDH1A1POLBMEN1 | |
| SCHEMBL23943823 | 0.89 | EGLN2 (0.31) | KMT2ATSHRALDH1A1POLB | |
| SCHEMBL7832550 | 0.84 | KMT2A (0.32) | KMT2ATSHRALDH1A1POLBMAPK1 | |
| SCHEMBL23943835 | 0.83 | — | — | |
| SCHEMBL23944460 | 0.82 | ALDH1A1 (0.31) | KMT2ATSHRALDH1A1POLB | |
| SCHEMBL23944462 | 0.81 | EGLN2 (0.39) | KMT2ATSHRALDH1A1POLB | |
| SCHEMBL23944159 | 0.80 | EGLN2 (0.39) | — | |
| SCHEMBL7833588 | 0.80 | ENPP1 (0.36) | KMT2ATSHRALDH1A1POLBMAPK1 | |
| SCHEMBL4814293 | 0.79 | KMT2A (0.33) | KMT2ATSHRALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227491-A1 | DEUTERATED TRIAZOLOPYRIMIDINES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-11-12 | — | — | WO | disclosed |