Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25615670 | 0.95 | CA2 (0.44) | EPHX1CA2KDM1ACA1MEN1 | |
| SCHEMBL19168536 | 0.86 | EPHX1 (0.42) | EPHX1CA2CASP2KDM1ADPP7 | |
| SCHEMBL21230926 | 0.81 | KDM1A (0.36) | KDM1AMEN1HTTKMT2A | |
| SCHEMBL18665149 | 0.80 | MEN1 (0.43) | EPHX1CA2KDM1ACA1MEN1 | |
| SCHEMBL21473435 | 0.79 | KDM1A (0.37) | KDM1A | |
| SCHEMBL21477768 | 0.79 | KDM1A (0.37) | KDM1A | |
| SCHEMBL13488628 | 0.75 | EPHX1 (0.47) | EPHX1CASP2DPP7ZDHHC20ZDHHC2 | |
| SCHEMBL23419432 | 0.74 | KDM1A (0.33) | KDM1A | |
| SCHEMBL22645874 | 0.74 | EPHX1 (0.41) | EPHX1CA2CASP2DPP7CA1 | |
| SCHEMBL21064892 | 0.73 | KDM1A (0.64) | EPHX1CASP2KDM1AZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227537-A1 | DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION | Modernatx, Inc (US) | 2020-11-12 | — | — | WO | disclosed |