Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19174253 | 0.95 | CA2 (0.42) | EPHX1CA2CA1MEN1HTT | |
| SCHEMBL19233108 | 0.86 | EPHX1 (0.41) | EPHX1CA2CASP2CA1MEN1 | |
| SCHEMBL18665159 | 0.81 | MEN1 (0.42) | EPHX1CA2CA1MEN1HTT | |
| SCHEMBL19176325 | 0.80 | CHRNB2 (0.31) | — | |
| SCHEMBL22645876 | 0.74 | EPHX1 (0.42) | EPHX1CA2CASP2DPP7CA1 | |
| SCHEMBL31344275 | 0.73 | EPHX1 (0.45) | EPHX1CASP2ZDHHC20ZDHHC2NAAA | |
| SCHEMBL18665165 | 0.71 | ALDH1A1 (0.36) | CA2CA1MEN1KMT2APPARA | |
| SCHEMBL27453925 | 0.71 | CA2 (0.35) | CA2 | |
| SCHEMBL19169196 | 0.71 | EPHX1 (0.40) | EPHX1CASP2DPP7HTTZDHHC20 | |
| SCHEMBL19771875 | 0.70 | CES2 (0.38) | CA2CA1MEN1KMT2APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227537-A1 | DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION | Modernatx, Inc (US) | 2020-11-12 | — | — | WO | disclosed |