Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18641719 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNATHRATHRBPRKCA | |
| SCHEMBL25418208 | 0.97 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL25417070 | 0.97 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL25419620 | 0.97 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL24627743 | 0.96 | ALDH1A1 (0.43) | ALDH1A1LMNATHRATHRBPRKCA | |
| SCHEMBL19138876 | 0.95 | ALDH1A1 (0.40) | ALDH1A1LMNATHRATHRBPRKCA | |
| SCHEMBL24627705 | 0.95 | ALDH1A1 (0.43) | ALDH1A1LMNATHRATHRBPRKCA | |
| SCHEMBL24628059 | 0.94 | THRA (0.42) | ALDH1A1LMNATHRATHRBPRKCA | |
| SCHEMBL24627759 | 0.93 | ALDH1A1 (0.41) | ALDH1A1LMNATHRATHRBPRKCA | |
| SCHEMBL24627551 | 0.93 | THRA (0.41) | ALDH1A1LMNATHRATHRBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227537-A1 | DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION | Modernatx, Inc (US) | 2020-11-12 | — | — | WO | disclosed |