SCHEMBL22645918

SCHEMBL22645918

CCCCCCCCC(CCCCCCC)OC(=O)CCCCCCCN(CCO)CC(O)CCCCCC(=O)OCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.45
PRKCE Q02156 2/20 0.45
PRKCQ Q04759 2/20 0.45
PRKCD Q05655 2/20 0.45
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
DNM1 Q05193 1/20 0.42
DGKA P23743 1/20 0.42
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ENPP2 Q13822 1/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20500902 1.00 PRKCA (0.45) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL27388656 0.96 LMNA (0.49) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL23137079 0.95 MAPT (0.43) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL27373210 0.94 MAPT (0.42) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL30884610 0.94 PRKCA (0.45) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL25485449 0.93 MAPT (0.50) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL25491600 0.93 MAPT (0.50) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL25480033 0.93 MAPT (0.50) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL25528219 0.92 LMNA (0.50) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL25531486 0.92 LMNA (0.50) PRKCAPRKCEPRKCQPRKCDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020227537-A1 DIFFERENTIALLY EXPRESSED IMMUNE CELL MICRORNAS FOR REGULATION OF PROTEIN EXPRESSION Modernatx, Inc (US) 2020-11-12 WO disclosed