Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676578 | 0.86 | HRH3 (0.51) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL5692250 | 0.84 | CYP3A4 (0.51) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL4425225 | 0.83 | CYP3A4 (0.50) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL1581156 | 0.83 | CYP3A4 (0.67) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL3846866 | 0.83 | CYP3A4 (0.67) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL4422581 | 0.83 | CYP3A4 (0.50) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL262239 | 0.83 | CYP3A4 (0.67) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL23513654 | 0.82 | HRH3 (0.47) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL20093553 | 0.82 | HRH3 (0.47) | HRH3HRH4ALDH1A1MEN1GLA | |
| SCHEMBL14279284 | 0.81 | ALDH1A1 (0.58) | HRH3HRH4ALDH1A1MEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150989-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2023-05-18 | — | — | US | disclosed |
| US-11332461-B2 | 2-(1H-pyrazol-3-yl) phenol compound and use thereof | BEIJING JIALIN PHARMACEUTICAL INC. (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20200354342-A1 | 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF | BEIJING JIALIN PHARMACEUTICAL INC. (CN) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332461-B2 | 2-(1H-pyrazol-3-yl) phenol compound and use thereof | VHL, PAH, TP53 | HRH3 4304/4885HRH4 4206/4885ALDH1A1 456/4885 |
| US-20200354342-A1 | 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF | VHL, PAH, TP53 | HRH3 4304/4885HRH4 4206/4885ALDH1A1 456/4885 |
| US-20230150989-A1 | HERBICIDAL MALONAMIDES | DDT, DHRS9, CA9 | HRH3 199/4885HRH4 331/4885ALDH1A1 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.