Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22647978 | 0.90 | RORC (0.35) | NTRK1DHODHPRSS12RORCPFKFB3 | |
| SCHEMBL22637297 | 0.85 | PFKFB3 (0.41) | NTRK1PFKFB3KDM4EMEN1ALDH1A1 | |
| SCHEMBL29430649 | 0.85 | PFKFB3 (0.41) | NTRK1PFKFB3KDM4EMEN1ALDH1A1 | |
| SCHEMBL22647986 | 0.84 | NTRK1 (0.37) | NTRK1DHODHRORCCREBBPKDM4C | |
| SCHEMBL22648195 | 0.83 | NTRK1 (0.36) | NTRK1DHODHRORCCREBBP | |
| SCHEMBL22647920 | 0.83 | RORC (0.33) | RORCCREBBPKDM4C | |
| SCHEMBL22647935 | 0.83 | NTRK1 (0.37) | NTRK1DHODHRORCCREBBPKDM4E | |
| SCHEMBL22647973 | 0.82 | NTRK1 (0.35) | NTRK1DHODHRORCCREBBPKDM4E | |
| SCHEMBL22647968 | 0.81 | NTRK1 (0.38) | NTRK1DHODHRORCCREBBPKDM4E | |
| SCHEMBL24929582 | 0.81 | KMO (0.33) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225569-A1 | PHENYL-SULFAMOYL.BENZOYC ACIDS AS ERAP1 MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2020-11-12 | — | — | WO | disclosed |