Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920490 | 1.00 | ACHE (0.41) | ACHETSHRHPGDALDH1A1TP53 | |
| SCHEMBL11920459 | 0.92 | TSHR (0.46) | ACHETSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL11920464 | 0.92 | ACHE (0.46) | ACHETSHRHPGDALDH1A1TP53 | |
| SCHEMBL22340414 | 0.87 | TSHR (0.44) | ACHETSHRHPGDALDH1A1TP53 | |
| SCHEMBL3821048 | 0.87 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL13346929 | 0.86 | ACHE (0.48) | ACHETSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL24212798 | 0.84 | TSHR (0.42) | ACHETSHRHPGDALDH1A1TP53 | |
| SCHEMBL10033496 | 0.84 | ACHE (0.42) | ACHETSHRHPGDALDH1A1TP53 | |
| SCHEMBL12922582 | 0.84 | TSHR (0.45) | ACHETSHRHPGDALDH1A1TP53 | |
| SCHEMBL12111976 | 0.83 | TSHR (0.57) | ACHETSHRHPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227264-A1 | FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS | FACEBOOK TECHNOLOGIES, LLC (US) | 2020-11-12 | — | — | WO | disclosed |