Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398146 | 0.84 | ALDH1A1 (0.44) | KMT2AMEN1CYP1A2TDP1CASP3 | |
| SCHEMBL5398141 | 0.84 | ALDH1A1 (0.44) | KMT2AMEN1CYP1A2TDP1CASP3 | |
| SCHEMBL5398176 | 0.84 | ALDH1A1 (0.44) | KMT2AMEN1CYP1A2TDP1CASP3 | |
| SCHEMBL14256476 | 0.80 | CYP1A2 (0.50) | KMT2AMEN1CYP1A2TDP1CASP3 | |
| SCHEMBL6520640 | 0.73 | CYP1A2 (0.47) | KMT2AMEN1CYP1A2CASP3ALDH1A1 | |
| SCHEMBL12478036 | 0.73 | LMNA (0.47) | KMT2AMEN1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL11726171 | 0.73 | LMNA (0.47) | KMT2AMEN1CYP1A2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5967158 | 0.73 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5967154 | 0.73 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL12834808 | 0.72 | CYP1A2 (0.50) | KMT2AMEN1CYP1A2CASP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| WO-2020227588-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354404-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | DNPEP, PEPD, ANPEP | KMT2A 4615/4885MEN1 242/4885CYP1A2 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.