Sugi Predict

Sugi Predict / Compounds / SCHEMBL22650209

SCHEMBL22650209

SCHEMBL22650209

CC1(C)OB(c2cccc(-c3cccc(-c4nc(-c5cccnc5)nc(-c5cccnc5)n4)c3)c2)OC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIPG Q9Y5X9 4/20 0.42
▸ LPL P06858 3/20 0.42
▸ CHRNB2 P17787 2/20 0.39
▸ CHRNA5 P30532 2/20 0.39
▸ CHRNA4 P43681 2/20 0.39
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ MAPT P10636 3/20 0.39
▸ TP53 P04637 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22649960 0.91 LIPG (0.51) LIPGLPLSMN1; SMN2MAPTTP53
SCHEMBL22418958 0.90 LIPG (0.46) LIPGLPLALDH1A1CYP1A2CYP3A4
SCHEMBL5527674 0.89 LIPG (0.45) LIPGLPLALDH1A1CYP1A2CYP3A4
SCHEMBL5533629 0.89 LIPG (0.45) LIPGLPLALDH1A1CYP1A2CYP3A4
SCHEMBL29653662 0.89 LIPG (0.47) LIPGLPLALDH1A1CYP1A2CYP3A4
SCHEMBL5529229 0.89 LIPG (0.47) LIPGLPLALDH1A1CYP1A2CYP3A4
SCHEMBL19106590 0.88 LIPG (0.57) LIPGLPLSMN1; SMN2MAPTTP53
SCHEMBL17725966 0.86 LIPG (0.53) LIPGLPLMAPTALDH1A1KDM4E
SCHEMBL29767884 0.86 LIPG (0.53) LIPGLPLMAPTALDH1A1KDM4E
SCHEMBL17721061 0.86 LIPG (0.53) LIPGLPLMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873294-B2 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2024-01-16 — — US disclosed
US-11873294-B2 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2024-01-16 — — US disclosed
US-20200354347-A1 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices VALIANT CO., LTD. (CN) 2020-11-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354347-A1 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices NLRP1, OCIAD2, OCIAD1 LIPG 3089/4885LPL 3021/4885CHRNB2 2850/4885
US-11873294-B2 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices NLRP1, OCIAD2, OCIAD1 LIPG 3089/4885LPL 3021/4885CHRNB2 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.