SCHEMBL5533629

SCHEMBL5533629

CC1(C)OB(c2cccc(-c3cc(-c4cccnc4)cc(-c4cccnc4)c3)c2)OC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 5/20 0.45
LPL P06858 4/20 0.45
MEN1 O00255 1/20 0.45
PSIP1 O75475 1/20 0.45
AXL P30530 1/20 0.45
MKNK1 Q9BUB5 1/20 0.45
MKNK2 Q9HBH9 1/20 0.45
CYP2A6 P11509 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
EPHX2 P34913 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
BACE1 P56817 3/20 0.42
CYP11B1 P15538 4/20 0.41
CYP11B2 P19099 4/20 0.41
KMO O15229 1/20 0.41
PGR P06401 1/20 0.41
CYP17A1 P05093 2/20 0.41
CYP19A1 P11511 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5527674 1.00 LIPG (0.45) LIPGLPLMEN1PSIP1AXL
SCHEMBL22418958 0.98 LIPG (0.46) LIPGLPLMEN1PSIP1AXL
SCHEMBL29653662 0.97 LIPG (0.47) LIPGLPLMEN1PSIP1AXL
SCHEMBL5529229 0.97 LIPG (0.47) LIPGLPLMEN1PSIP1AXL
SCHEMBL5527589 0.95 LIPG (0.46) LIPGLPLMEN1PSIP1AXL
SCHEMBL21311948 0.95 LIPG (0.46) LIPGLPLMEN1PSIP1AXL
SCHEMBL12129647 0.94 LIPG (0.45) LIPGLPLMEN1PSIP1AXL
SCHEMBL5529453 0.92 LPL (0.49) LIPGLPLMEN1PSIP1AXL
SCHEMBL5531896 0.92 LIPG (0.54) LIPGLPLMEN1PSIP1AXL
SCHEMBL18682140 0.89 LIPG (0.41) LIPGLPLMEN1PSIP1AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445881-B1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM BOE TECHNOLOGY GROUP CO LTD (CN) 2017-11-15 EP disclosed
US-8865905-B2 Organic compounds GENERAL ELECTRIC COMPANY (US) 2014-10-21 US disclosed
US-8865905-B2 Organic compounds GENERAL ELECTRIC COMPANY (US) 2014-10-21 US disclosed
US-20130217882-A1 ORGANIC COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2013-08-22 US disclosed
US-20130217882-A1 ORGANIC COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2013-08-22 US disclosed
US-8426601-B2 Process for making organic compounds and the organic compounds made therefrom GENERAL ELECTRIC COMPANY (US) 2013-04-23 US disclosed
US-8426601-B2 Process for making organic compounds and the organic compounds made therefrom GENERAL ELECTRIC COMPANY (US) 2013-04-23 US disclosed
US-20120178938-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2012-07-12 US disclosed
US-20120178938-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2012-07-12 US disclosed
US-8178682-B2 Process for making organic compounds and the organic compounds made therefrom GENERAL ELECTRIC COMPANY (US) 2012-05-15 US disclosed
US-8178682-B2 Process for making organic compounds and the organic compounds made therefrom GENERAL ELECTRIC COMPANY (US) 2012-05-15 US disclosed
US-20100331547-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2010-12-30 US disclosed
US-20100331547-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331547-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM CYP4F11, BCL6, CYP2F1 LIPG 4487/4885LPL 3831/4885MEN1 1136/4885
US-20120178938-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM CYP2F1, CYP4F2, CYP1B1 LIPG 4128/4885LPL 3614/4885MEN1 3160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.