SCHEMBL22650232

SCHEMBL22650232

Cn1nccc1/N=N/c1sc(/N=N/c2ccc(O)c(Cl)c2)nc1-c1cccs1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RPS6KB2 Q9UBS0 1/20 0.33
BRD4 O60885 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22650266 0.86 MEN1 (0.40) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL22650274 0.84 KDR (0.40) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL22650271 0.83 MAPT (0.37) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL15049243 0.79 PTGS1 (0.46) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL16232517 0.79 PTGS1 (0.46) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL22650233 0.74 MEN1 (0.48) MEN1KMT2A
SCHEMBL25925933 0.68 PTGS1 (0.41) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL18250390 0.66 KMT2A (0.49) BRD4MEN1KMT2A
SCHEMBL22754696 0.63 MEN1 (0.35) BRD4PTGS1PTGS2MEN1KMT2A
SCHEMBL13505630 0.62 INSR (0.54) BRD4PTGS1PTGS2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT FUJIFILM CORPORATION (JP) 2020-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT CYP1B1, CYP1A1, NAT1 RPS6KB2 2972/4885BRD4 2321/4885PTGS1 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.