SCHEMBL22754696

SCHEMBL22754696

CN1N=CCC1/N=N/c1sc(/N=N/c2ccc(O)c(Cl)c2)nc1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GBA1 P04062 1/20 0.35
HPGD P15428 1/20 0.35
BRD4 O60885 1/20 0.32
ADORA2A P29274 4/20 0.32
ADORA1 P30542 3/20 0.32
HTT P42858 1/20 0.31
MMP14 P50281 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDR P35968 2/20 0.31
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22650266 0.76 MEN1 (0.40) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL22650271 0.68 MAPT (0.37) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL13505630 0.64 INSR (0.54) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL22650232 0.63 RPS6KB2 (0.33) MEN1KMT2ABRD4PTGS1PTGS2
SCHEMBL22650274 0.62 KDR (0.40) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL10598861 0.61 PTGS1 (0.62) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL10598869 0.61 PTGS1 (0.62) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL21125070 0.60 PTGS1 (0.67) MEN1LMNAMAPTKMT2ATDP1
SCHEMBL14255077 0.60 PTGS2 (0.46) MEN1LMNAMAPTMAPK1KMT2A
SCHEMBL30595630 0.60 PTGS2 (0.46) MEN1LMNAMAPTMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3747956-A1 STAINING COMPOSITION, STAINED ARTICLE, AND AZO DYE FUJIFILM Corporation (JP) 2020-12-09 EP disclosed