Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 13/20 | 0.53 |
| ▸ | DRD1 | P21728 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | DRD5 | P21918 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28870119 | 0.81 | PTGER1 (0.44) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL2557802 | 0.79 | L3MBTL1 (0.56) | HPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL8523471 | 0.79 | HRH1 (0.54) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL8584676 | 0.78 | CCNB2 (0.57) | SMN1; SMN2DRD2L3MBTL1HTR1AADRA1D | |
| SCHEMBL21538649 | 0.78 | HPGD (0.50) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL10601013 | 0.77 | DRD2 (0.69) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL4003173 | 0.77 | DRD2 (0.54) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL19733216 | 0.76 | HPGD (0.67) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL12129191 | 0.76 | DRD1 (0.63) | HPGDSMN1; SMN2HRH1DRD1DRD2 | |
| SCHEMBL11349591 | 0.76 | HPGD (0.61) | HPGDSMN1; SMN2HRH1DRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225330-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2020-11-12 | — | — | WO | disclosed |