Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650380 | 0.86 | HDAC2 (0.36) | RETRORCGAAPPIADDB1 | |
| SCHEMBL22650347 | 0.86 | PKM (0.36) | RETRORCPPIADDB1CRBN | |
| SCHEMBL29224968 | 0.83 | GFER (0.43) | RETRORCGAACASP6GFER | |
| SCHEMBL16491319 | 0.78 | RECQL (0.39) | RORCGAA | |
| SCHEMBL16491317 | 0.73 | AAK1 (0.43) | RORCGAAUSP30 | |
| SCHEMBL22650582 | 0.71 | RET (0.42) | RETRORCHDAC3 | |
| SCHEMBL20069300 | 0.71 | SMN1; SMN2 (0.41) | RETRORCDRD2 | |
| SCHEMBL12628008 | 0.70 | RET (0.40) | RETRORCDRD2 | |
| SCHEMBL22650581 | 0.70 | RET (0.40) | RETRORCCRBNHDAC2HDAC1 | |
| SCHEMBL23122999 | 0.69 | RET (0.39) | RETRORCDDB1CRBNDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |