Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 5/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20069300 | 0.87 | SMN1; SMN2 (0.41) | MAPTALDH1A1LMNARETRORC | |
| SCHEMBL22650582 | 0.84 | RET (0.42) | MAPTALDH1A1LMNARETRORC | |
| SCHEMBL12628008 | 0.83 | RET (0.40) | ALDH1A1LMNARETRORC | |
| SCHEMBL22650345 | 0.83 | RET (0.35) | GFERCASP6RETRORCGAA | |
| SCHEMBL20354566 | 0.81 | GFER (0.54) | GFERCASP6MAPTALDH1A1LMNA | |
| SCHEMBL23122999 | 0.80 | RET (0.39) | RETRORC | |
| SCHEMBL20069047 | 0.80 | RET (0.44) | MAPTALDH1A1LMNARETRORC | |
| SCHEMBL22246083 | 0.78 | RET (0.42) | GFERCASP6RETGPR119KMT2A | |
| SCHEMBL19701820 | 0.78 | GPR119 (0.40) | MAPTALDH1A1RETRORCGPR119 | |
| SCHEMBL20069024 | 0.78 | GPR119 (0.55) | RETGPR119HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |