Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462406 | 0.91 | F10 (0.49) | F10PTGS2TYK2JAK2JAK1 | |
| SCHEMBL2343226 | 0.91 | F10 (0.49) | F10PTGS2TYK2JAK2JAK1 | |
| SCHEMBL31035634 | 0.80 | ALDH1A1 (0.51) | — | |
| SCHEMBL75939 | 0.80 | F10 (0.49) | F10PTGS2 | |
| SCHEMBL1269266 | 0.80 | ALDH1A1 (0.51) | — | |
| SCHEMBL2343208 | 0.78 | AKR1C3 (0.49) | — | |
| SCHEMBL12280261 | 0.78 | PIK3CA (0.43) | F10PTGS2PIK3CAMTORPIK3R1 | |
| SCHEMBL12279805 | 0.77 | AKR1C3 (0.50) | — | |
| SCHEMBL3297140 | 0.75 | PTGS2 (0.48) | F10PTGS2TYK2JAK2JAK1 | |
| SCHEMBL8285973 | 0.75 | PTGS2 (0.48) | F10PTGS2TYK2JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |