⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797238 | 0.72 | ALDH1A1 (0.45) | — | |
| SCHEMBL7288077 | 0.70 | ADRA2B (0.45) | — | |
| SCHEMBL8562544 | 0.70 | HPGD (0.35) | — | |
| SCHEMBL7283649 | 0.70 | ALDH1A1 (0.48) | — | |
| SCHEMBL12958735 | 0.70 | — | — | |
| SCHEMBL8562063 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL7286892 | 0.68 | NPC1 (0.46) | — | |
| SCHEMBL31451633 | 0.68 | GAA (0.39) | — | |
| SCHEMBL7287173 | 0.67 | PARP10 (0.41) | — | |
| SCHEMBL22650909 | 0.67 | CRBN (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040446-A | CDK inhibitors | 基因泰克公司 | 2025-05-27 | — | — | CN | disclosed |
| US-20220296595-A1 | CDK INHIBITORS | GENENTECH, INC. | 2022-09-22 | — | — | US | disclosed |
| CN-114364675-A | CDK inhibitors | 上海齐鲁锐格医药研发有限公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-3966213-A1 | CDK INHIBITORS | Qilu Regor Therapeutics Inc. (CN) | 2022-03-16 | — | — | EP | disclosed |
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |