Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 20/20 | 0.53 |
| ▸ | CDK4 | P11802 | 16/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 8/20 | 0.53 |
| ▸ | CCND3 | P30281 | 6/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CSF1R | P07333 | 5/20 | 0.45 |
| ▸ | CCNK | O75909 | 3/20 | 0.45 |
| ▸ | CDK9 | P50750 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CCND1 | P24385 | 4/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650550 | 0.89 | CDK4 (0.42) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650546 | 0.88 | CDK4 (0.42) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650865 | 0.86 | CDK4 (0.55) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650558 | 0.86 | CDK6 (0.47) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650949 | 0.82 | CDK6 (0.45) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650543 | 0.78 | CDK4 (0.44) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650547 | 0.78 | CDK6 (0.43) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650859 | 0.77 | CDK4 (0.51) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650956 | 0.77 | CDK6 (0.59) | CDK6CDK4CCNA2CCND3CDK2 | |
| SCHEMBL22650636 | 0.77 | CDK4 (0.64) | CDK6CDK4CCNA2CCND3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |