Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 17/20 | 0.55 |
| ▸ | CDK6 | Q00534 | 15/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.55 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | CDK9 | P50750 | 3/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.55 |
| ▸ | CCNK | O75909 | 2/20 | 0.55 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | CCNH | P51946 | 1/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.55 |
| ▸ | CCND3 | P30281 | 3/20 | 0.53 |
| ▸ | CCND1 | P24385 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650610 | 0.88 | CDK6 (0.61) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650431 | 0.86 | CDK6 (0.53) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650558 | 0.85 | CDK6 (0.47) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650949 | 0.81 | CDK6 (0.45) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650547 | 0.79 | CDK6 (0.43) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650550 | 0.78 | CDK4 (0.42) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650956 | 0.78 | CDK6 (0.59) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650629 | 0.78 | CDK6 (0.41) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL22650751 | 0.77 | CDK6 (0.52) | CDK4CDK6CCNA2CDK2CDK9 | |
| SCHEMBL29491169 | 0.77 | CDK6 (0.52) | CDK4CDK6CCNA2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |