SCHEMBL22650438

SCHEMBL22650438

Nc1ccc(N2CC3CC2CN3)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 13/20 1.00
CHRNA4 P43681 13/20 1.00
CHRNB4 P30926 1/20 0.61
CHRNA3 P32297 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5036737 1.00 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5372714 1.00 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL5043622 0.99 CHRNB2 (0.97) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5037226 0.84 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL6629065 0.84 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5374465 0.84 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5379236 0.82 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL22988895 0.82 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5037429 0.82 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL7250932 0.82 CHRNB2 (0.97) CHRNB2CHRNA4CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020224568-A1 CDK INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2020-11-12 WO disclosed