Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583728 | 0.88 | ESR2 (0.44) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL22650348 | 0.87 | NR1H2 (0.46) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL29990901 | 0.87 | MAPT (0.46) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL22650415 | 0.87 | MAPT (0.46) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL29709677 | 0.87 | NR1H2 (0.46) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL1663275 | 0.86 | GALR2 (0.43) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL26629245 | 0.86 | NR1H2 (0.46) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL25088458 | 0.85 | ENPP2 (0.43) | NR1H2MAPTALDH1A1LMNAENPP2 | |
| SCHEMBL3312798 | 0.85 | MAPT (0.45) | NR1H2MAPTALDH1A1LMNAESR2 | |
| SCHEMBL31129834 | 0.85 | NR1H2 (0.46) | NR1H2MAPTALDH1A1LMNAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021189-A1 | OXYGEN-CONTAINING FUSED TRICYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海拓界生物医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |