Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21112108 | 0.86 | GPR119 (0.52) | HRH3GPR119ALDH1A1EGFRMAPT | |
| SCHEMBL30643674 | 0.86 | GPR119 (0.52) | HRH3GPR119ALDH1A1EGFRMAPT | |
| SCHEMBL27095193 | 0.84 | GPR119 (0.52) | HRH3GPR119ALDH1A1EGFRMAPT | |
| SCHEMBL26641265 | 0.83 | GPR119 (0.46) | HRH3GPR119ALDH1A1PTPN11MAPT | |
| SCHEMBL20037632 | 0.83 | MAPT (0.43) | HRH3GPR119ALDH1A1ALOX5APFEN1 | |
| SCHEMBL255485 | 0.82 | MAPT (0.44) | HRH3GPR119ALDH1A1PTPN11MAPT | |
| SCHEMBL29491152 | 0.82 | MAPT (0.44) | HRH3GPR119ALDH1A1PTPN11MAPT | |
| SCHEMBL22650819 | 0.80 | HRH3 (0.39) | HRH3L3MBTL1 | |
| SCHEMBL31727825 | 0.79 | GPR119 (0.46) | HRH3GPR119ALDH1A1MAPTMEN1 | |
| SCHEMBL1393764 | 0.79 | MAPT (0.56) | GPR119ALDH1A1PTPN11MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |