SCHEMBL22650711

SCHEMBL22650711

c1ccc(-n2c3sc4[nH]c5cc6ccccc6cc5c4c3c3ccc4ccccc4c32)cc1

nearest known ligand 0.30

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.30
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30
PDE7A Q13946 1/20 0.30
PDE7B Q9NP56 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22650898 0.89 KIF11 (0.38) CDK4CCND1PDE7APDE7BKIF11
SCHEMBL22650728 0.85 CDK4 (0.33) CDK4CCND1PDE7APDE7BSIRT2
SCHEMBL22650662 0.82 PDPK1 (0.32) CYP1A1CYP1B1
SCHEMBL22650653 0.74 L3MBTL1 (0.44)
SCHEMBL22650655 0.73 KDM4E (0.38) PDE7A
SCHEMBL19916022 0.73 AHR (0.37) CDK4CCND1CYP1B1PDE7APDE7B
SCHEMBL20966299 0.73 CDK4 (0.35) CDK4CCND1CYP1B1PDE7APDE7B
SCHEMBL22650650 0.72 L3MBTL1 (0.39) CYP1A1CYP1B1
SCHEMBL22650657 0.71 L3MBTL1 (0.36) CYP1A1CYP1B1
SCHEMBL19382775 0.70 KIF11 (0.39) CDK4CCND1PDE7APDE7BKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020226295-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-11-12 WO disclosed