Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 20/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 19/20 | 0.51 |
| ▸ | CDK2 | P24941 | 18/20 | 0.51 |
| ▸ | CDK1 | P06493 | 7/20 | 0.51 |
| ▸ | CDK7 | P50613 | 7/20 | 0.51 |
| ▸ | CDK9 | P50750 | 7/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650953 | 0.90 | JAK2 (0.45) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL29491157 | 0.87 | MAPT (0.45) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650775 | 0.79 | CDK4 (0.44) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650429 | 0.70 | CCND1 (0.40) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650859 | 0.70 | CDK4 (0.51) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650734 | 0.70 | CDK6 (0.48) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650857 | 0.69 | CDK6 (0.45) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650548 | 0.68 | CDK4 (0.41) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL22650958 | 0.68 | CDK4 (0.42) | CDK4CDK6CDK2CDK1CDK7 | |
| SCHEMBL18288984 | 0.67 | CDK4 (1.00) | CDK4CDK6CDK2CDK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |